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Eukesh (खँल्हाबल्हा | योगदान) No edit summary |
Eukesh (खँल्हाबल्हा | योगदान) No edit summary |
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क्यान्सरं छुं नं उमेरया मनुयात असर यायेफु। अथे जुसाँ आपालं क्यान्सरया रिस्क दँ नापं अप्वया वनि। <ref name="Cancer Research UK">{{cite web | last =Cancer Research UK | title =UK cancer incidence statistics by age | month=January | year=2007 | url =http://info.cancerresearchuk.org/cancerstats/incidence/age/ | accessdate =2007-06-25 }}</ref> सकल मनु मृत्युया १३% क्यान्सरं सी।<ref name="WHO">{{cite web | last =WHO | authorlink =World Health Organization | title =Cancer | publisher =World Health Organization |month=February | year=2006 | url =http://www.who.int/mediacentre/factsheets/fs297/en/ | accessdate =2007-06-25 }}</ref>
सकल थें क्यान्सरत जेनोमया म्यालिग्नेन्ट ट्रान्सफर्मेसनं पलिस्था जुइ। <ref name="Kinz">{{cite book | author = Kinzler, Kenneth W.; Vogelstein, Bert | title = The genetic basis of human cancer | edition = 2nd, illustrated, revised| language = | publisher = McGraw-Hill, Medical Pub. Division | location = New York | year = 2002 | page = 5| isbn = 978-0-07-137050-9 | url = http://books.google.co.uk/books?id=pYG09OPbXp0C| chapter=Introduction |chapterurl=http://books.google.co.uk/books?id=pYG09OPbXp0C&pg=PA5&dq=%22from+defects+in+oncogenes%22&lr=&ei=EJ8pSujtDYWKygSqj8ikBw#PPA6,M1}}</ref>
Genetic abnormalities found in cancer typically affect two general classes of genes. Cancer-promoting ''[[oncogene]]s'' are typically activated in cancer cells, giving those cells new properties, such as hyperactive growth and division, protection against [[programmed cell death]], loss of respect for normal tissue boundaries, and the ability to become established in diverse tissue environments. ''[[Tumor suppressor gene]]s'' are then inactivated in cancer cells, resulting in the loss of normal functions in those cells, such as accurate DNA replication, control over the [[cell cycle]], orientation and adhesion within tissues, and interaction with protective cells of the [[immune system]].
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